These markers may pinpoint quiescent MM cells capable of fueling recurrences.
Conversely, pMHC dextramer of the 8E variant that we believe to have a KD of ∼2 mM was capable of low-level staining in the presence of 50 nM dasatinib.
This shows that the VAMP-depleted area around the injection site, spanning ~2.5 mm, was capable of initiating and sustaining seizures, and that this area's cellular electrophysiology is directly relevant to the epileptic syndrome.
A few miles inland from the beach were 88-mm guns capable of supporting the machine guns and mortars that were placed in the dunes and villas and that constituted the Germans' first line of defense.
It can grow on most soils in semi-natural, disturbed, eroded, and degraded habitats, tolerates an extensive range of precipitation (500 3500 mm), and is capable of surviving a lengthy (6 8 months) dry season (Francis and Lowe 2000).
Hence, an experimental sparging hydrolysis reactor using a mullite tube (ID 70 mm) was constructed capable of holding 0.3 0.5 kg (1.5 2.5 × 10−3 kg mol) CaBr2 forming a melt with a maximum 0.08 m (8 cm) depth.
The 120 mm actuator is capable of deformations up to approximately 160° in both the pure bending and pure twisting modes and of approximately 80° for both twisting and bending in the combined twisting and bending mode of actuation.
In this model, MM cells are capable of metastasizing to the second implanted bone but not to any murine organs.
Early work by Hamburger and colleagues showed that bone marrow cells from MM patients were capable of in vitro colony formation [ 67].
Interestingly, treatment of 24 hr cultures with KCl (40 mM), which is capable of depolarizing immature neurons, led to a significant upregulation of c-FOS and SATB1 within 24 hr.
