The results of the tests on the foam-sand mixture samples with various mixing ratios demonstrated that the variation in damping ratios is a function of foam mass.
Mixture samples with known proportions can help determine experimental reproducibility and discover technical artifacts introduced by the measurement process by comparison of the expected to observed proportions.
Relative affinities of candidate biotin derivatives with unknown molar quantities in each mixture sample were consistent with those estimated by a homogenous method using their purified counterparts as samples.
Their in silico synthesized mixture expression profiles, obtained by multiplying the measured pure tissue expression profiles by the proportion of the tissue subset in a given mixture sample, were highly correlated with the experimentally measured expression profiles for the mixtures.
Solvents in each reaction mixture were removed under reduced pressure to give a residual that served as a mixture sample after the wash with ethyl ether (additional file 5).
In the experimental approach, a representative mixture sample possessing candidate ligands with moderate differences in both their quantities and affinities is needed, and the practical quantity of the target can be slightly higher than an optimized one to enhance universal applicability to different mixture samples.
In the case of mechanical properties, red mud is effective in enhancement of the compressive and flexural strength; the compressive and flexural strength of SCM mixture samples prepared with red mud at 50% of replacement ratio are higher than those of other samples.
Therefore, this new method was firstly tested with each mixture sample containing a single candidate ligand as the primary component (the affinities of other compounds as the secondary components are not estimated), and then tested with each mixture sample containing multiple candidate ligands.
Each PMFS was made by mixing a mixture sample at an indicated quantity with its exogenous reference ligand (BMPL or BPDEDA) at a fixed quantity, both in methanol, to have a final reference ligand at 200 μM in each PMFS.
For favorable efficiency in the optimization of PMFS composition ratios, the concentration of a reference ligand (or the content of a mixture sample) in the PMFSs, together with the quantities of the PMFSs in the competitive binding systems, can be fixed so that only the contents of the mixture (or the concentrations of the reference ligand) in the PMFSs need to be optimized.
