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In vivo, osteocyte cells under normal conditions, contact a complex mixture of secreted 'extracellular matrix' (ECM) proteins called the bone matrix.
Gastric fluid consists of a mixture of secreted soluble and exfoliated cellular proteins from the entire gastric mucosa – including regions that cannot be adequately assessed by fibreoptic gastroscopy.
Furthermore, a distinctive shoulder was observed at about λexc = 330 nm and λem = 450 nm indicating that the signal results from a mixture of secreted furanocoumarins [ 39].
Airway mucus is a heterogeneous mixture of secreted polypeptides, cells and cellular debris that is present in the airway surface lining fluid subphase or tethered at the fluid surface by oligomeric MUC (mucin) complexes [ 1, 2].
We had expected to find large differences between the responses to ex vivo stimulation with BCG and PPD, given that BCG is a live bacterium and PPD is a mixture of secreted proteins from M.tb.
Previous studies have shown that C-26 conditioned medium is a complex mixture of secreted proteins, including cytokines, growth factors, and signaling molecules, some of which can potentially play a role in myogenic program and muscle wasting [ 5, 24].
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Further, in mature Leishmania infections the SV is forced open and becomes blocked with parasites embedded in promastigote secretory gel (PSG), a viscous mixture of phosphoglycans secreted by the parasites (Stierhof et al., 1999; Rogers et al., 2002; 2004).
The only measurements required are those of metabolic fluxes observable through the measurement of secreted metabolites.
Surfactant is a complex mixture of lipoproteins synthesised, secreted and recycled by type II alveolar cells.
Vogel et al. found that cells expressing DDR1 showed robust receptor phosphorylation when Matrigel, a mixture of ECM proteins secreted by Engelbreth Holm Swarm mouse sarcoma cells, was added to the culture medium [17].
The high relevance of T. reesei for the production of economically feasible second generation biofuels from cellulosic agricultural waste instead of food crops still requires considerable improvement of the efficiency of the cellulase mixture secreted [ 45].
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