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Exact(5)
An alternative explanation for the reduced infectivity of parasites evolved on a mixture of hosts is that they have had less time to adapt to each of their hosts [ 20].
These conclusions rely on the critical assumption that parasites that had evolved on a mixture of hosts behave as one generalist strain, as opposed to a mix of specialized strains.
All of these clusters contained a mixture of hosts, and it would be possible to speculate that the transmission of serovar Australis to humans in that area is via the native rodent population indigenous to that area.
Under this hypothesis, even without any cost to adaptation, it is expected that parasites selected on a mixture of hosts would initially exhibit a lower success on a single host line because of the lower time spent within this host, but ultimately reach similar infectivity if selection is carried out for a long enough time.
Finally, to estimate the cost of specialization, we defined an index of the evolutionary response of specialized parasites as the relative difference between infectivity of parasites that had evolved in a single regime and were tested on one of the host's isofemale lines, and the infectivity of generalists (that had evolved on a mixture of hosts) on the same isofemale line.
Similar(55)
Each was a mixture of host DNA and the genes of a rare, dangerous virus.
From this ecological vantage, the body's economy is regulated by a mixture of host and 'unrelated' genomes and thus the notion of a circumscribed, self-defined entity ― designated 'the self' ― requires qualification.
The pace of HIV disease progression is multifactorial - a mixture of host and pathogen genetics combined with factors such as the immune response and viral adaptation.
In both Chad and the DRC, we serve a shifting mixture of host communities, refugee camps, and IDPs simultaneously.
An alternative strategy is to sequence an acknowledged mixture of host and graft, then use in silico methods to classify the individual sequence reads.
As the endosymbionts cannot be grown outside of their trypanosomatid host, we proceeded to shotgun sequence the mixture of host and bacterial DNA directly from the cultures, without any enrichment or separation of cells or DNA.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com