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Overall, our findings suggest that chronic exposure to waterborne Cd and Zn in mixture may induce additive reproductive toxicity, essentially by disrupting estrogen-mediated functions in fish.
Thus, Figure 6 demonstrates clearly that the mixture may induce a response that is higher than is possible to induce by one of the compounds.
In terms of design and data assessment, this type of study differs from those discussed so far, because not all components present in the mixture may induce the effect chosen for analysis.
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The induction of specific outcomes of PCBs, such as a transient increase in gladularity, may reflect the fact that the PCB mixture used in this study, namely, Aroclor 1254, is a complex mixture of > 40 congeners that may induce a variety of effects that are not evoked by estrogen.
The dosage of SP for each mixture was carefully selected as over dosage may induce bleeding and strength retardation.
These results suggest that the exposure to mixture of pirimiphos methyl, chlorpyrifos, temephos and malathion may induce DNA damage, decrease in AChE activity, hepatotoxicity as well as nephrotoxicity.
Because SDS may induce artificial Aβ oligomerization [35], in separate experiments, cross-linked Aβ40 oligomer mixtures were analyzed by both SDS-PAGE and size-exclusion chromatography, which confirmed the presence of bona fide dimers, trimers, and tetramers (data not shown).
Prenatal exposure to endocrine-disrupting chemicals (EDCs) may induce weight gain and obesity in children, but the obesogenic effects of mixtures have not been studied.
It may induce nothing more than vertigo.
If they desensitise some people, they may induce empathy in others.
Too little medication may induce withdrawal symptoms like sweating, sleeplessness and abdominal discomfort.
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