Sentence examples for mixed with leptin from inspiring English sources

SCID/beige mice were implanted with MCF7 cells alone, MCF7 cells mixed with control shRNA obASCs, or MCF7 cells mixed with leptin shRNA obASCs for 36 days.

Protein lysates were isolated with radioimmunoprecipitation assay (RIPA) buffer (Pierce; Thermo Scientific) from primary tumors formed with MCF7 cells, MCF7 cells mixed with control shRNA obASCs, or MCF7 cells mixed with leptin shRNA obASCs.

Meanwhile, tumors formed with MCF7 cells mixed with leptin shRNA obASCs showed no difference from MCF7 cells without prior exposure to ASCs (Fig.  6c).

In contrast, dsRed expression was not visible in tumors formed with MCF7 alone or mixed with leptin shRNA obASCs (Fig.  5d).

Mice injected with MCF7 cells mixed with control shRNA obASCs (2.0 ± 0.20 %) had significantly more metastasis compared to mice injected with MCF7 cells mixed with leptin shRNA obASCs (0.5 ± 0.04 %) (P <0.05; Fig.  7c-d; Additional file 7).

Assessment of the tumors showed increased expression of SERPINE1, MMP-2, and IL-6 in tumors formed with control shRNA obASCs mixed with leptin (P <0.05; Fig.  6a; Additional file 6).

In order to investigate the effects of leptin silencing on tumorigenesis, MCF7 cells were implanted alone or mixed with control shRNA obASCs or leptin shRNA obASCs into the mammary fat pad of SCID/beige mice.

To assess the direct impact of leptin inhibition in obASCs on BCC proliferation, MCF7 cells were injected alone or mixed with control shRNA obASCs or leptin shRNA obASCs into SCID/beige mice.

With leptin injections, the animals stopped eating and lost weight.

Cawthorne would supplement infants' formula with leptin during the period in which their metabolisms are being calibrated.

Recombinant leptin therapy potently decreases food intake and body weight in aleptinemic individuals with leptin gene mutations.