When mixed, wild-type XLF and XRCC4 form even larger supra-molecular complexes.
e, Average recovery rate ( ± s.e.m.) of mice from mixed wild-type and NBC blastocyst transfers; NS, not significant, P > 0.05 (unpaired, two-tailed t-test).
These observations were further expanded by 3H-fluconazole sequestration assay, whereby mixed wild-type biofilms contained higher levels of matrix-bound fluconazole than those formed with GtfB-defective strain (P < 0.001, Fig. 6e); as expected, GtfB supplementation restored fluconazole sequestration in the matrix of mixed biofilms with gtfB∆ mutant.
In addition, with the transgenic parasites, strain-specific protection can be analyzed in mice against a challenge of mixed wild-type P. berghei and transgenic parasites.
Since microarray data from a mixed wild-type background were not available as a control, it was necessary to use the pure 129 and B6 wild-type datasets as controls for the Crx Nrl double mutant.
Five of the 8 patients were found at some time to have mixed, wild-type and mutant, populations.
DOI: http://dx.doi.org/10.7554/eLife.08698.016 To determine if mTOR acts within Tfh cells, we constructed and immunized 50 50 mixed wild-type: chino bone marrow chimeras with SRBC.
To determine whether SOX17 acts cell autonomously, we mixed wild-type NANOS3-mCherry hESCs with the SOX17 null hESCs in 1 1 ratio during induction of hPGCLCs by cytokines.
These mixtures together with non-mixed wild-type RNAs were used for RNA-seq library preparation.
A remarkable finding of our study was that C. elegans L1 larvae displayed very low complex I and citrate synthase activities when compared to a mixed stage wild type population, indicating a low mitochondrial content at this developmental stage.
