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They include tumours of single or mixed tissue types, potentially affecting any part of the body, with a risk of malignant transformation.
Images were excluded from analysis if cores were folded, absent, incomplete, or contained mixed tissue types.
An important consideration when generating FTIR spectra from biospecimens such as sputum is that cells will often be derived from mixed tissue types which can lead to spurious results [ 32].
Unlike the gill library from the treatment group, which appears to represent mixed tissue types, there were no transcript or gene expression patterns that indicate the presence of mixed tissue in the gill library from the control group.
This confirms that de novo assembly of short read RNA-seq data is capable of recovering close to half of the genes in a nuclear genome with mixed tissue types of leaves and flower buds.
For each patient, the correct rate, false alarm rate, and the omission rate are calculated for each pure tissue and mixed tissue types by comparing results with expert labeling.
Similar(52)
D-type cyclins were effectively suppressed in mixed tissue type MSTO-211H, leading to cell cycle arrest at sub G1/G1 phase.
The number of all tissue-centric contextual gene sets were 51 with | ∪ T k Annot (T k ) | = 169, while 175 contextual gene sets were cancer generic with | A n n o t(Cancer)|=413 (the rest 52 gene sets with mixed tissue type interactions were not considered in this process).
On histopathological examination, the 11-mm nodular tumour had the features of a mesenchymal tumour with abundant matrix with small spindle-shaped cells and granular calcifications and a cell-rich component of irregular cells with foci of multinucleated osteoclast-like cell in accordance with a phosphaturic mesenchymal tumour of the mixed connective tissue type [ 7].
It is also relatively robust against annotation errors as mixing two tissue types together will create a bimodal expression profile for at least some of genes and AGEP can accept that as a feature of the (mixed) tissue class whereas methods based single summary statistic would generate values that are not correct for either tissue types of the mix.
The other tissue types show mixed results with some diversity measures showing significant reductions compared with ARs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com