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Mixed population studies including adults and children were included.
Where there was a mixed population, studies rarely indicated any differences between people with different diagnoses.
A summary of the major fracture outcomes in the community and mixed population studies can be found in Table 4. Measurements of BMD were eligible for inclusion in five studies [ 17, 18, 21, 23, 26, 27].
Five instruments (AI, NEI-VFQ, VA LV VFQ, DLTV and SRA-VFP) have been administered with a stroke population embedded within larger mixed population studies or a relatively small sample [ 30, 32, 33, 41, 42].
The data from these three series also differ in terms of gender distribution, with a greater [C]WAY-100635 BP reported in women in the two mixed population studies [ 12, 13].
Although the 40 descriptive studies in mixed populations were potentially generalisable to a wider population, many of the mixed population studies were appraised as having a high risk of outcome assessment bias due to their reliance on database reporting.
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The pre-specified possible sources of inter-study heterogeneity were: cancer type, ethnicity of population (Caucasian, East Asian, South Asian, African or Mixed population), study design (hospital-based case-control study, population-based case-control study or nested case-control study), sample size (≥500 or <500) and HWE violation (violated or not violated).
A mixed population study [ 50] found statistically significantly improved reach and ability to stand and walk, as well as a trend towards improved transfers.
The ten studies identified in the review included refugee [ 38- 43, 43, 45- 47], IDP [ 41, 42] and mixed-population studies [ 44].
These articles were subdivided into 34 studies with a total of 5,391 patients comprising a potentially mixed population (most studies provide no information about how many children were included), and 13 studies concerning only pediatric populations, totaling 1,243 patients aged ≤ 8 years.
a Mixed-risk population studies include children with individual differences in risk of severe RSV disease and studies of the general population even when a minority of the study population includes high-risk children.
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