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The mixed extract of A. fistulosum and V. mandshurica also included high levels of iron (884%% of the RDA).
The mixed extract of A. fistulosum and V. mandshurica was rich in vitamins (E, B1, B2, niacin, and folic acid) and essential minerals (calcium, iron, and zinc).
Our results suggest that the mixed extract of A. fistulosum and V. mandshurica improved lipid metabolism via the up-regulation of PPAR-γ, UCP-2, and adiponectin expression and down-regulation of leptin in adipose tissue.
The oral administration of the mixed extract of A. fistulosum and V. mandshurica (AFE + VME) significantly reduced body weight, fat mass, and adipocyte size, and improved serum triglyceride, total cholesterol, and leptin levels in high-fat-diet-induced obese mice.
DA-9801, comprising a mixed extract of Dioscoreae rhizoma and Dioscorea nipponica Makino, is a new standardized extract currently being evaluated for diabetic peripheral neuropathy in a phase II clinical study.
Although the anti-obesity effects of these constituents has not been demonstrated in this work, these results suggest that these phenolic compounds may synergistically contribute to the anti-obesity and hypolipidemic effects of the mixed extract of A. fistulosum and V. mandshurica.
Similar(51)
We observed the effects of mixed extract on body weight, fat mass, serum lipid levels, and mRNA expression levels of lipid metabolism-related genes in the adipose tissue of mice.
The mixed extract contains 22%% of the recommended daily allowance (RDA) of carbohydrate (72.2 g/100 g), 21 % of the RDA of protein (11.5 g/100 g), 3%% of the RDA of fat (1.7 g/100 g), and non-detectable levels of cholesterol.
To evaluate potential toxicity of the mixed extract, we measured serum markers of liver and kidney injuries.
The mixed extract containing 50 µg of protein was dissolved in 0.5 mol l−1 Tris-HCl (pH 8.5) containing 8 mol l−1 urea, 2.5 mmol l−1 ethylenediaminetetraacetic acid, and 10 mmol l−1 dithiothreitol, and incubated for 1.5 hours at 37°C.
The yield of the mixed extract was 11.25% % (w/w).
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