Sentence examples for mitotic localization to from inspiring English sources
Its mitotic localization to the spindle pole bodies (SPBs), kinetochores and along the spindle remained unchanged (Fig. 1A).
In order to further analyze the mitotic localization of Dnmt2 we used the developing larval brain, which contains a high number of proliferating neuroblasts giving rise to ganglion mother cells (GMC).
This also shows that the meiotic and mitotic localization of these proteins differ, as in embryos they localize in different patterns, while in oocytes Mps1 and Polo were found together at both the filaments and meiotic kinetochores [20].
Next, we generated constructs containing mutagenized Ran-binding domains of RanBP2 and importin β1 (RanBP2-mt and Imp- β1-mt, respectively) to determine whether the lack of Ran binding in one partner affected the mitotic localization of the other partner.
The mitotic localization of Dnmt2 was reminiscent of microtubule (MT) structures that form the spindle apparatus during cell divisions.
It is possible that the mitotic localization pattern of Dnmt2 reflects the distribution of the protein into daughter cells via nuclear envelope vesicles [34].
Furthermore, Cdk1, ERK2, and Plk1 cooperate in the phosphorylation of CEP55 during mitosis, which is required for the correct mitotic localization of CEP55 and its function during cytokinesis [9].
The differential mitotic localization of Aurora A and Aurora B is dictated by a distinct repertoire of interaction partners.
Taken together, these observations demonstrated that the knockdown of importin β1 reduces the mitotic localization of RanBP2 and RanGAP1 in vertebrate cells.
Yet, a human mitotic phosphorylation motif associated with protein localization to the mitotic apparatus was recently identified in RIC8A, suggesting a role for RIC8A in mitosis [ 10].
These results indicate a strong interdependency between pericentrin and Cep215 for their localization to mitotic centrosomes and that either protein only partially contributes to γ-tubulin recruitment.
