Sentence examples for mitotic commitment to from inspiring English sources

These environmental changes also accelerated mitotic commitment to reduce cell size at division after 120 min.

Exposure to nitrogen stress inhibited TORC1 activity and advanced mitotic commitment to promote division at a reduced cell size.

In this case, negative regulation of TORC1 signaling boosts mitogen-activated protein kinase (MAPK) to promote mitotic commitment [ 21, 22].

Cells still advanced mitotic commitment and reduced their size at division under these conditions of abundant carbon, suggesting that the response to the change in medium was indeed nitrogen specific.

The cdc2.1w mutant strain was used to address whether the increase in AMPKαSsp2 phosphorylation was a secondary consequence of accelerated mitotic commitment rather than the alteration in nitrogen supply.

Aurora-A and its substrates complete the assignments in cell division coordinately through phosphorylation reactions, such as centrosome maturation, spindle assembly, mitotic commitment and cytokinesis [2].

Rapamycin treatment rescued the AMPKα ssp2.Δ mitotic commitment phenotype.

Cells deleted for AMPKα ppk9 accelerated mitotic commitment in the same way as wild-type cultures.

In S. pombe, Tor participates in other cellular functions including nutrient signaling [ 29], cell growth and differentiation [ 30], mitotic commitment [ 31], and sexual development [ 11].

The SPB is known to recruit a number of kinases and phosphatases that modify its subunits, and these modifications play a critical role in regulating mitotic commitment and meiotic progression [ 22– 25].

In agreement with this, we find that Tsc1/2 and Rhb1 are involved in the control of mitotic commitment following nitrogen stress in fission yeast, suggesting that an AMPK-Tsc-TORC1 signaling module exists in this model organism.