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Runx2 mitotic binding is associated with increased H3K4 dimethylation [ 26].
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The incomplete overlap of TAF9B and OLIG2 peaks may in part represent intrinsic differences between progenitor cells and post-mitotic neurons, since the OLIG2 binding was performed with neuralized EBs enriched for progenitor cells while TAF9B mapping was done with EBs enriched for post-mitotic motor neurons.
The effect of these point mutations on Rad51 binding was not altered by nocodazole-induced mitotic arrest.
Condensin binding to mitotic chromosomes is also promoted by mitosis-specific kinases (Nakazawa et al. 2008; St-Pierre et al. 2009; Tada et al. 2011).
Not all bindings are interchangeable.
Stalling of cells in G1 precluded the nuclear localization of the DBD5 in HEK293 and U2OS cells (Figure 3C), supporting the interpretation that binding to mitotic chromatin was necessary for its nuclear retention later in interphase.
Mitotic activity is rare.
The mitotic spindle is a biological structure composed of microtubules.
Mitotic activity is low.
Mitotic dysregulation is implicated in cellular aging.
As a result, mitotic progression is restricted.
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