Sentence examples for mitochondrial transit from inspiring English sources

Mitochondrial transit peptides were identified using the program TargetP [133].

Transport into the organelle is mediated by a mitochondrial transit signal following the N-terminal cleavable signal peptide of nicastrin.

In some cases transit peptide-like domains of plastid proteins are also recognised as mitochondrial transit peptides by the program TargetP (http://www.cbs.dtu.dk/services/TargetP/) [133].

45 of thee 185 candidate proteins possess both an N-domain coding for a putative mitochondrial transit peptide and a C-domain coding for an endoplasmic reticulum (ER) targeting signal (Figure 1).

Several mitochondrial genes have eQTL mapping between 172.7 and 173.3 Mb in Qrr1; ten of these genes possess a mitochondrial transit peptide, which is required for transport of the proteins across the mitochondrial membrane.

The C-domain is predicted as a standard secretion signal containing an n-, h-, and c-region (SignalP 3.0 probability  = 0.9), whereas the N-domain receives a prediction as a mitochondrial transit peptide (TargetP probability  = 0.3).

Mitochondrial-targeting transit peptides were predicted in GSIIB sequences from C. reinhardtii, Volvox carteri f. nagariensis and Scenedesmus obliquus (see Additional file 5).

Studies in patients have suggested that the clinical phenotypes of some mitochondrial diseases might transit from one disease to another (e.g., Pearson syndrome [PS] to Kearns-Sayre syndrome) in single individuals carrying mitochondrial (mt) DNA with a common deletion (∆mtDNA), but there is no direct experimental evidence for this.

Recombination events and exon-shuffling have been discussed by various authors as possibly involved in the addition of sequences encoding transit peptides (mitochondrial targeting signals) to nuclear genes for mitochondrial proteins.

TargetP determines the putative subcellular localization based on the presence of chloroplast transit peptide, mitochondrial targeting peptide, or secretory pathway signal peptide.

In addition, genes encoding mitochondrial proteins, and/or include transit peptide domains, are significantly overrepresented among downregulated genes in mu10 (see Figure  5).