Sentence examples for mitochondrial operation from inspiring English sources

Oncogenic K-Ras and H-Ras were shown to promote autophagy, which supports transformation and cell survival mainly through the maintenance of mitochondrial operation and ATP levels.

In this third mode of operation, H2O2 efflux from mitochondria is negligible compared with modes 1 or 2. Our next focus is to understand in detail the sites and mechanisms of O2− production under these three modes of mitochondrial operation and thereby infer where and how O2− is produced in vivo.

Because changes in mtDNAn can affect the integrity, assembly, and operation of the mitochondrial respiratory chain [ 41, 42], it is conceivable that the mitochondrial function or capacity is impaired in obese subjects.

The British Parliament voted in February last year to allow clinical trials of Mitochondrial Transfer, a process designed to eliminate the passing of mitochondrial disease from mother to child.

More recent genetic studies have also suggested that operation of a complete mitochondrial TCA cycle is not required for the development of the asexual stages in the related murine parasite, Plasmodium berghei[ 18, 19].

However, in the animal cells monensin induces mitochondrial damage without apparent change in the operation of the Golgi structure [ 43].

Normal mtDNAn and the integrity of the mtDNA molecule account for a functional mitochondrial genome,and are critical for assembly and operation of the respiratory chain [ 41, 42].

If this process is impaired, mitochondrial disorder will ensue.

The differentiation of myoblasts into myotubes is accompanied by a pronounced rise in mitochondrial content [ 1], which is a process highly dependent on the intricate co-operation of both the nuclear and the mitochondrial genomes.

The mitochondrial membrane potential (MMP), a driving force for the operation of ATP synthase (complex V) to produce ATP, is dependent on the ETC activity [ 21].

The outcome of mitochondrial quality control is not only reliant on the efficient operation of the core homeostatic mechanisms but also in the effective interaction of mitochondria with other cellular components, namely the nucleus.