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It is tempting to speculate that every distinct TA-containing MOM protein has its own role in creating an appropriate microenvironment for mitochondrial interactions with other cell structures.
Mitochondrial interactions with the nuclear genome represent one of life's most important co-evolved mutualisms.
Curiosity in BCL-2 family - mitochondrial interactions led to the identification that the sphingolipid pathway plays a crucial role in BCL-2 family function.
In this special issue we also address roles of mitochondrial interactions which are central to the physiological processes involved in malignant transformation.
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Mitochondrial interaction partners include genes of α-proteobacterial origin and the ribosomal DNA.
But cellular metabolic energy production is critically dependent on nuclear mitochondrial interaction [33].
To account for these results, we suggest that Akt phosphorylates mitochondria-bound HKII, thereby preventing the ability of G-6-P to reduce HK mitochondrial interaction.
We demonstrate that the redox state modulates the mitochondrial interaction of MAPKs to MAPKKs by oxidation of conserved cysteine domains of MAPKs to sulfinic and sulfonic acid; this biochemical mechanism determines MAPKs differential activation and traffic to nuclei and ultimately, sustains the phenotype of LP07 tumor cells.
Interestingly, the ER was recently shown to participate in autophagy initiation through a mitochondrial interaction [ 193 ▪ ].
Wheat is an excellent plant species for nuclear mitochondrial interaction studies due to availability of large collection of alloplasmic lines.
Mitochondrial binding occurred preferentially over the vegetative 'meront' stages of the parasite, which bulged into the cytoplasm, thereby increasing the membrane surface available for mitochondrial interaction.
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