Sentence examples for mitochondrial fragmentation during from inspiring English sources

Unlike 13510/3665 mitochondria, drp-1 mitochondria failed to fragment, consistent with an essential role for Drp-1-mediated mitochondrial fragmentation during apoptosis in Drosophila.

In addition to mitochondrial fragmentation during apoptosis [4], extensive mitochondrial remodelling happens in response to metabolic changes (reviewed in [5]).

Our results demonstrate that METH induces mitochondrial fragmentation during the early stages of apoptosis (Fig. 3; Fig. 4), which is consistent with reports that this process of fragmentation occurs early in the cell-death pathway [39], [57], [58].

Moreover, induction of Reaper and Hid appears to result in mitochondrial fragmentation during Drosophila cell death.

Using genetic mutants and RNAi-mediated knockdown of drp-1, we find that Drp-1 not only regulates mitochondrial fission in normal cells, but mediates mitochondrial fragmentation during programmed cell death.

The field of mitochondrial dynamics blossomed when the processes of cristae remodeling and mitochondrial fragmentation during apoptosis were discovered (Scorrano et al., 2002; Frank et al., 2001; Martinou et al., 1999).

In addition, mitochondrial fragmentation occurs during apoptosis [28], which could be induced by Aβ.

In conclusion the light scattering data measured in this study report on mitochondrial fragmentation early during apoptosis.

Oxygen-glucose deprivation (OGD) of neurons grown in culture induced a dual-phase mitochondrial fragmentation profile: (i) fragmentation during OGD with no apoptosis activation, followed by fusion of mitochondrial networks after reoxygenation and a (ii) subsequent extensive fragmentation and apoptosis activation that preceded cell death.

Global mitochondrial fragmentation is observed during mitosis, where it is thought to facilitate the segregation of the reticulum into daughter cells 40, 41, and during apoptosis, where the smaller fragments seem to accelerate the release of cytochrome c 42, 43.

The mechanism(s) involved in participation of PHB in the mitochondrial fusion/fission during the mitochondrial fragmentation leading to apoptosis may be explained by altered processing of OPA1 [ 38; our unpublished study].