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Since the balance between cell proliferation and differentiation relies on the mitochondrial state of the cell, we compared the mitochondrial development and the differentiation potential of y- and a-iPSCs.
Carbon catabolite repression down-regulates the expression of genes that encode enzymes involved in gluconeogenesis, the Krebs cycle, respiration, mitochondrial development, and the utilization of carbon sources other than glucose, fructose or mannose [ 11].
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The PPR proteins are another large family with significant roles in plastid and mitochondrial development in plants (reviewed in [ 33], and [ 34]).
Here we induced chloroplast and mitochondrial development in rice vascular sheath cells through constitutive expression of maize GOLDEN2-LIKE genes.
When the scientists examined tissue samples from different portions of the exercised animals' brains, they found markers of upwelling mitochondrial development in all of the tissues.
Trypanosomes have been shown to rely on mitochondrial metabolism only in the insect vector since the absence of kDNA has been shown to hamper mitochondrial development.
Rather, Akt1 functions through its downstream targets, activating mTOR and inhibiting Foxo3a which have roles in the regulation of mitochondrial metabolism, myocyte development, and gene expression (Zhou et al., 2015).
Target genes bearing these binding sites are known to be important for various cellular processes, such as stress response, cell growth and development, and mitochondrial gene expression.
The importance of mitochondrial polymorphisms in cancer development and risk is intimately related to evolutionary haplogroups, and has recently been a contentious area of research.
To define the role of mitochondrial fission in muscle development and repair, we have generated a transgenic mouse line that overexpresses the fission-inducing protein Drp1 specifically in skeletal muscle.
Our current study aims to investigate if the mitochondrial electron transport chain is uncoupled during early cancer development, and whether mitochondrial uncoupling affects p53 translocation to mitochondria.
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