Sentence examples for mitochondrial calcium from inspiring English sources

Mitochondrial calcium uptake capacity modulates neocortical excitability.

Gu, L., Larson-Casey, J.L. & Carter, A.B. Macrophages utilize the mitochondrial calcium uniporter for profibrotic polarization.

The relevance of mitochondrial calcium exchange in vivo has been controversial.

Giorgi, C. et al. Mitochondrial calcium homeostasis as potential target for mitochondrial medicine.

The authors conclude that cardiomyocyte mitochondrial calcium exchange is a prominent mitochondrial regulatory mechanism in cardiac disease.

Mitochondrial calcium (mCa2+) has a central role in both metabolic regulation and cell death signalling, however its role in homeostatic function and disease is controversial1.

Conditional deletion of the mitochondrial sodium calcium exchanger NCLX in adult mouse hearts caused sudden death owing to mitochondrial calcium overload and necrotic cell death.

Potential role of BNIP3 in cardiac remodeling, myocardial stiffness, and endoplasmic reticulum: mitochondrial calcium homeostasis in diastolic and systolic heart failure.

We also fused APEX to the N or C terminus of the mitochondrial calcium uniporter (MCU), a recently identified channel whose topology is disputed.

In a September 2010 paper, Mootha's group described using the MitoCarta inventory to identify the first protein specifically required for mitochondrial calcium uptake.

Calcium ion interactions with mitochondria are crucial for their function, and deregulation of mitochondrial calcium levels has been implicated in several human diseases.