Challenges include the requirement for valid exposure and outcome data, identification of, and access to, adequate data sources, and mitigating limitations including bias and confounding.
Though there is little formal research with which to compare our results, the issues raised by authors previously cited [ 1- 7] are similar across continents and countries, thus mitigating limitations 2 and 3. Regarding limitation 4, it would appear from their responses that many informants had no difficulty being frank and open with the field investigators.
The results show that, the operating temperature and pressure, and the inlet water flowrate and thickness of the PTL are the critical parameters for mitigating mass transport limitation at high current densities.
Enriching the observational record will go some way to eliminating, or at the very least mitigating, the biases and limitations of each proxy (Gergis and Fowler 2009; Jones and Mann 2004).
However, because targeting VEGF alone has reported limitations in mitigating tumor growth, the study of other angiogenic factors is markedly growing [ 4].
The above findings indicate that FRP can benefit corn cropping for higher yield through mitigating soil temperature and moisture limitations to corn growth in cool high-latitude rainfed areas.
Therefore, it would be attractive to fabricate lipid-PLGA hybrid NPs, which combine the desirable characteristics of both liposome and PLGA NPs, meanwhile mitigating or even avoiding the aforementioned limitations.
An analysis of the relative importance of the three mitigating factors showed that passive diffusion limitations due to ionization and molecular size accounted for 69% of the model variance and metabolism 27%; all other mitigating factors accounted for the remaining 4% of model variance.
However, mitigating measures to enhance validity and minimise self-report limitations such as miscomprehension, measurement error and conscious bias [34, 35] were adopted.
These limitations are inherent in qualitative research and mitigating steps were taken with the sampling strategy that drew from a variety of clinicians (nurses, pharmacists, occupational therapists, physiotherapists, and dieticians) from both participating sites.
They write: "Even when mitigating factors, such as the remote location and the practical limitations imposed by the Department of Immigration and Border Protection are considered, many aspects of the IHMS health service fall well below accepted standards for clinical practice and are unnecessarily dangerous".
