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It appears that in patients that have already gained weight, as is the case for patients in the amantadine and sibutramine groups, these factors were not predictive for potential weight loss or weight gain in response to the addition of a weight mitigating agent.
We tested the hypothesis that because of their flavor-enhancing properties, mushrooms could be used as a healthy substitute for meat and a mitigating agent for sodium (salt) reduction without reduction in sensory appeal among consumers.
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Because of its negative effect on environment and the host animal nutrition, mitigation of enteric CH4 fermentation in ruminant livestock, including the use of various mitigating agents, such as ionophores [ 4], organic acids [ 5], fatty acids [ 6], methyl coenzyme M reductase inhibitors [ 7], and oil [ 8] has been extensively researched.
The adaptability of manufacturing techniques for AgNPs and their easy reconstitution into distinct media have prompted further research into the hypothetical impact of nanoparticles as antimicrobial, antiviral, and mitigating agents.
[ 2, 3, 6] Five variables were identified as predictors for weight loss in patients treated with olanzapine and weight mitigating agents, 2 of which were baseline variables that existed in patients treated with olanzapine before the introduction of any weight-mitigating agent.
[ 9] A comprehensive review of weight mitigating agents and their use during treatment with antipsychotics has been published recently by Baptista and colleagues.
The aim is not to compare different weight mitigating agents, but to evaluate patients' characteristics and changes in their eating behaviors during treatment.
While Figure 1 summarizes the results, it is not intended to suggest direct comparisons of the efficacies of the different weight mitigating agents used in our analyses.
These predictors may be useful in identifying subgroups of patients who may be susceptible to the effect of weight mitigating agents during olanzapine treatment.
Identification of patient subgroups with different degrees of susceptibility to the effect of weight mitigating agents during olanzapine treatment may aid clinicians in treatment decisions.
The aim is neither to extract predictors for weight change during olanzapine monotherapy nor to compare different weight mitigating agents, but to evaluate patients' characteristics and changes in their eating behaviors during treatment with olanzapine and weight mitigating agents in overweight patients.
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