As with α-SMA, these results again suggest that the biology of fibroblasts from DC patients is exquisitely sensitive to the mitigating actions of cAMP.
Therefore, it is important not only to understand the various failure modes, and their root causes and effects, but also to develop real-time automated diagnostics tools that can capture the early signatures of fault evolution for mitigating actions.
It was assessed that the availability of the ITER CIS, with appropriate mitigating actions applied, meets the project availability requirement for the system.
The ultimate aim of this activity is the definition, on the basis of this assessment, of a list of preventive or mitigating actions (such as relocation, shielding or preventive maintenance) for the most high-risk components.
This understanding could then be used as the basis for the development of tailored mitigating actions that target the specific source of the oscillation (e.g. a specific generator) and not just the symptoms of this oscillation (e.g. the power flow on a certain corridor).
It notes that mitigating actions are needed but lacking.
These need time and the 30-minute warning limits the range of mitigating actions that National Grid can take.
"We've had a number of fairly tepid steps taken to address the problem, but in reality, those mitigating actions are simply not sufficient," Mr. Johns said.
The savings, £10m of which are due to be delivered this year, were fuelled by reduced newsprint prices and "ongoing cost mitigating actions".
This better understanding improves preventive and mitigating actions taken in specific circumstances.
