Jack Dolan, a spokesman for the American Council of Life Insurers, said, "There's always been the possibility that people would attempt to misuse the variable product and if there is anything illegal under way we certainly would want it prosecuted".
Similar leading causes to that found in our study were reported (in variable proportions): drug misuse (dose error, inadequate follow-up, drug interaction, administration error and contraindication), underuse (absence of prophylaxis) and overuse (inappropriate drug).
Australian New Zealand Clinical Trials Registry (ACTRN) registration number: ACTRN12611000579998 Treatment engagement and retention in residential drug rehabilitation settings for individuals with substance misuse and psychiatric comorbidities is variable [ 1- 4].
The 'lifestyle' variables including alcohol misuse, smoking and obesity were found to be poorly coded (e.g. only 4 people had a Read code for smoking) and were not included in further analyses.
Previous studies have shown that AUDIT-C can effectively identify alcohol misuse [ 22, 23]; therefore this variable was included in our analyses.
Alcohol use ≥14 units/week or previous alcohol misuse was used as a categorical variable in the model examining hepatic steatosis, but not that examining NAFLD.
Binary logisitic regression was used with the presence of the UHR state as dependent variable while multiple substance misuse and SOFAS scores were co-variates.
In regard to a mutidisciplinary study concept, the present study focused the investigation of possible alterations of certain EEG variables according to Ecstasy misuse.
Franzén et al. used admission to hospital for psychiatric illness, attempted suicide or substance misuse for either parent to create a 'psychosocial risk' variable [ 29].
Continued positive UTS for cannabinoids were tracked, however, to examine this variable as a potential predictor of opioid misuse as defined above.
Our findings also speak to the use and misuse of nonlinear modeling when there may be omitted variables.
