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This might be beneficial for EELS experiments that typically suffer from a limited amount of rotation angles (missing wedge problem) and where the number of measurement points is often kept low to avoid sample contamination.
While various ways have been developed to overcome the missing wedge problem (e. g., ref (101)), procedures that fully account for the missing wedge are still missing.
Due to limited tilt angles, ET reconstruction always suffers from the "missing wedge" problem.
In recent years, many algorithms have been proposed to deal with the "missing wedge" problem.
This is most effective in reducing reconstruction artifacts arising from the "missing wedge" problem.
In electron tomography, it is generally not possible to obtain the exact solution of the inverse problem outlined in Eq. (11), mostly because of the missing wedge problem.
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DOI: http://dx.doi.org/10.7554/eLife.03600.008 The orientation of our crystals prevented the full sampling of reciprocal space leading to systematic incompleteness (missing wedge or missing cone).
To address this problem, Förster et al proposed a constrained correlation measure with missing wedge corrections [ 11].
Despite the recent progress in the field of reconstruction and regularization techniques, the missing wedge artefacts remain untreated in most current reconstruction workflows in structural biology.
Fig. 5 Missing wedge reconstruction, processed with NAD. a A WBP reconstruction of aligned, noiseless projections with a 28 ° missing wedge.
Fig. 10 Missing wedge reconstruction processed with Weka. a The perfectly aligned, noiseless 28 ° missing wedge reconstruction from Fig. 5. b The same reconstruction but processed with Trainable Weka Segmentation.
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missing wedge mask
missing wedge artifact
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missing wedge effect
missing wedge correction
missing wedge elongation
missing regulator problem
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missing wedge electron
missing pyramid problem
missing heritability problem
missing wedge region
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