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Outcome variables were missing values (yes or no) for HADS-D at Years 2 and 3 for students entering year 1 and Years 5 and 6 for students entering year 4. The explanatory variable was HADS-D at Year 1 for Core Science students and Year 4 for Clinical students.
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A variety of analyses were performed, whereby options like 'fixed number of factors yes or no' and 'replace missing values by mean yes or no' were tested.
Furthermore, patients lost to follow-up were comparable to those available for analyses and our results were robust for imputing yes or no for missing values in a sensitivity analysis.
Before pregnancy: 13 missing values; Week 17: 13 missing values; Week 32: 3 missing values; 8 weeks after delivery: 5 missing values.
There were no missing values.
Thus, no missing values were used.
No imputation of missing values was performed.
We imputed missing values individually in the binomial outcomes of attitude (positive/negative) and combination of actual and planned uptake (yes/no) in the following manner.
Missing values were kept missing.
a2 missing values; b3 missing values; c10 missing values.
10 missing values; 2 missing values.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com