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Although 19 fragments harbor a new mutation profile, they can not be assigned to a new SHV number because of missing sequence information.
The Recombination Activation Gene 1 was split in two smaller fragments, as was Apolipoprotein B due to large amounts of missing sequence information in some species.
In 2010, Hanson et al. pointed out the dual problem of increasing number of proteins of unknown function produced by genome projects, facing the orphan enzymes missing sequence information [ 20].
One of the reasons for this heterogeneity may be caused by differences in the N e of the different vertebrate species, as the number of species included differs for each of the enzymes due to technical (e.g. missing sequence information) or biological reasons (e.g. absence of an enzyme).
In addition, OrMIPE1 1 shares significant sequence similarity with OlMIPB1 1 and OrMIPB1 1 in loop E. It should be noted that CnMIPE1 3 is missing sequence information corresponding to half of H4, loop D and most of H5 due to a gap in the available genomic sequence.
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Additionally, for exome and genome sequencing data, we included flanking intronic regions and developed a method to impute missing sequence data based on phylogenetic information.
We want to use secondary structure information wherever we have both residues in a base pair, but revert to primary sequence alignment when we are missing sequence data.
Only the be3 segment on VIIIβ persisted as a single copy but, waiting for information about missing sequences, this segment was also retained for further analysis and designated as EXT7.
We also found instances of genes incorrectly annotated as pseudogenes because Gnomon was unable to build a complete gene model due to missing or incorrect sequence information.
If the PPI information is missing, given the FASTA sequence information, one can make use of the STRING database [ 51].
First, for these SNPs we have a concordance between the position given by the genome sequence (information missing for uSNPs) and the RH data.
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losing sequence information
missing pathway information
lost sequence information
limited sequence information
need sequence information
less sequence information
missing sequence similarity
missing sequence composition
missing sequence encoding
missing sequence stretch
missing sequence coverage
missing sequence evolution
missing sequence region
missing race information
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