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Clinicians should bear in mind that in clinical practice, strict adherence to ICHD criteria would result in missing patients who likely do have CH and would benefit from treatment.
These associations were used to develop algorithms that may reduce the numbers needing screening whilst limiting the risk of missing patients who may be at risk if given TDF.
However, such a reliance on FISH testing alone can risk missing patients who overexpress HER2 but are not amplified on FISH.
Although both approaches resulted in missing patients who could benefit from the recommended treatment, the use of clinical measurements is more sensitive to screen for poorly treated patients.
The second limitation is that our study enrolled only cases diagnosed by the public health system, and could be missing patients who sought diagnosis and treatment from private providers.
Within our own study, unquantifiable errors or omissions, that are also likely to be small, will have included missing any non-fatal accidents or DSH that do not present to hospital, and similarly missing patients who leave the area of record, in this case Scotland, before experiencing harm-related events.
Similar(53)
The calculation also misses patients who were confirmed as Ebola cases, but then left the hospital before being discharged, says Andrew Rambaut, an evolutionary biologist who studies infectious disease at the University of Edinburgh in the United Kingdom.
It misses patients who don't have such a reaction.
We may also have missed patients who did have exposure.
Therefore, we could have missed patients who had more severe disease and died prior to hospital admission.
Calculating the scores for only those patients judged to be 'at risk' may potentially miss patients who actually are at risk.
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