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Patients were excluded in case of seropositivity of HIV or missing laboratory parameters at diagnosis.
Missing values (i. e. missing laboratory parameters) also could have created a selection bias.
Patients were excluded in case of seropositivity of human immunodeficiency virus (HIV), missing laboratory parameters at diagnosis, lost to follow-up or central nervous system lymphoma.
Similar(57)
Thirty-one (15.3%) patients of the whole cohort (n=202) could not be included into analyses due to at least one missing laboratory parameter at the time of surgical intervention.
21 Similar efforts were made to calculate the SAPS II score automatically in a retrospective cohort of 524 patients from an academic surgical ICU at University Hospital Giessen, Germany. 2 The study cohort had many missing laboratory values and clinical parameters required for SAPS II score calculation.
Second, as a retrospective study, missing laboratory data was inevitable.
Missing laboratory values were interpolated if adjacent values were present.
In addition, we excluded those with missing laboratory data.
Normal values were imputed in place of missing laboratory data.
There were some missing laboratory results due to laboratory reagent shortage, or administrative errors.
Clinical data were prospectively collected for each patient by using a case report form by the clinician and missing data and laboratory parameters were retrieved from the electronical medical and hospital records.
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