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As exposed in the method section, three analyses were carried out. 1) In the first one (primary one), vaccination is considered completed three weeks after injection and all influenza cases with missing injection date are treated as unvaccinated.
Since, during the pandemic, most reported influenza cases were vaccinated in the three weeks that preceded the consultation, considering missing injection date as belonging to the last three weeks, as was done in the first analysis, might be the more realistic option.
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There was a gradual increase in the number of children missing injections from one month to the next.
Six patients withdrew prematurely: three because of adverse events, one due to lack of efficacy and two for other reasons (missing injections during weeks 10 12 for one patient, and time interval was too long between injections for the second patient).
Data values represent number (percentage) of respondents who gave the indicated response as a reason for missing injections Comparing recorded against reported adherence showed that more children had higher reported adherence than recorded adherence at each time point as well as overall (90.2% vs 87.5%; Table 3a).
Any missed injection is a major concern.
Second, when calculating percentage adherence using the 'number of missed injections' questionnaire box selected, the midpoint value for each tick box was imputed, i.e. when the tick box '1-3 injections missed' was ticked, the value '2' was imputed.
The range of incubation times from midpoint of treatment, ignoring missed injections, with any type of growth hormone to onset of symptoms was 20.6 37.6 (mean 29.3) years.
The frequency of missed injections was estimated to be 0 in 36% of children, up to 1 per week in 25% of children, >1-2 per week in 16% of children and >2 per week in 23% of children.
Losing Art Start is a real shame and I know there will be many artists who graduate really missing that injection of faith into their fledgling practice," she told VICE.
For the most frequent cycle of fortnightly prescriptions, this reflects missing one injection or more every two months.
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