Sentence examples for missing heritability problem from inspiring English sources

If rare variants can be included, he believes, the missing heritability problem will disappear.

He concludes that these studies do not resolve the missing heritability problem.

Our three simulation studies suggest that at least part of the missing heritability problem of complex phenotypes may originate in misspecification of the phenotypic model.

It is generally accepted that there is a missing heritability problem.

The present article considers reasons for the missing heritability problem and possible solutions.

A third benefit is that GCTA provides insight into genetic architecture and the missing heritability problem.

To confirm the presence of molecular systems structures that may better explain missing heritability problems for T2D, we adopted a Systems Biology approach to studying T2D genetic risk gene networks as a whole rather than the risk genes individually.

Studies that look at the DNA of people with bipolar disorder have found some genetic risk factors, but bipolar disorder suffers from "missing heritability"—a problem with many psychiatric conditions where genes alone don't explain or predict who will develop a disease.

This suggests that searching for interaction effects may help solve the problem of missing heritability to some extent.

There are two main reasons for this: First, the problem of missing heritability and second, the limited identification and functional characterization of causal variants.

Thus known genetic effects account for about one-third of the familial relative risk of breast cancer, leaving two-thirds unaccounted for, a phenomenon referred to as the "problem of missing heritability".