Sentence examples for missing genotypes in from inspiring English sources

Imputation methods typically use a reference panel of densely genotyped haplotypes to predict the missing genotypes in a less densely genotyped study sample.

Tests for systematically missing genotypes in either cases or controls were performed to identify sample selection or genotyping problems preferentially affecting either group.

In order to reduce the bias caused by missing data, we did not include any subjects who had one or more missing genotypes in generating the GRS.

SNP rs356220 showed missing genotypes in nearly 18% of controls compared with <1% of cases (P = 4.73×10−15) suggesting a systematic problem in genotyping of this SNP in control samples, and it was therefore excluded from further analyses.

Since some of the data analysis methods (e.g., Principal Component Analysis or Support Vector Machines described below) require no missing data, we imputed missing genotypes in the SNP dataset and used it whenever these methods were employed.

Moreover, 39 HC (10.6%) were not allocated to a control cluster because of missing genotypes in at least one of the best determining SNPs, when dropped down the control SNP tree.

In addition to observed genotypes, our approach allows estimation of missing genotypes, resulting in substantial increases in power when genotyping resources are limited.

To assess population genetic structure, I excluded all individuals with more than five missing genotypes, resulting in 247 coyotes (16 in Ohio, 118 in contact zone, 113 in northeast zone).

The procedures for inference on HWE with missing genotypes discussed in this paper are implemented in the R-package HardyWeinberg (https://cran.r-project.org/web/packages/HardyWeinberg/index.html).html

Increasing allowed alignment mismatches helps overcome missing genotypes, inaccuracies in the reference genome, and errors in the sequence reads, but also results in increased erroneous sequence alignment, particularly when aligning shorter reads.

Dropping imputation for missing genotypes results in an even higher (r = 0.73) for correlation with the fraction of missing data.