Sentence examples for missing genotypes are from inspiring English sources

Cost-effective studies using sequence data can be achieved via pedigree-based genotype imputation in which some subjects are sequenced and missing genotypes are inferred on the remaining subjects.

Based on estimated parameters, missing genotypes are inferred.

First, missing genotypes are sampled based on allele frequencies estimated from reference haplotypes, and then an Expectation-Maximization (EM) algorithm is used to estimate parameter values.

The missing genotypes are imputed many times, leading to many completed data sets.

Here, we disregard true missingness and assume that all missing genotypes are attributable to allelic dropout.

In a second step, the genotyping data from the Dam, containing assigned and missing genotypes, are combined with all available genotyping data from the MGS, Offspring and Sire, and missing genotypes are filled in using LD information.

The potential genotyping errors and missing genotypes were inferred by using information from flanking marker data with the initial marker order.

Their missing genotypes were imputed using either Beagle or LDMIP from T densely genotyped candidates chosen from the whole pedigree.

The mutual intersection of all data sets yielded 19,372 diallelic, autosomal SNPs with experimentally determined genotypes (i.e., no imputation of missing genotypes was performed).

SNPs with ≥2 missing genotypes were excluded.

The overall rate of missing genotypes was 9%.