Sentence examples for missing gene is from inspiring English sources

To understand the role of any newly found human gene, researchers can identify the counterpart gene in mice, genetically engineer a strain of mouse that lacks the gene, and figure out from the mouse's defects what the missing gene is meant to do.

(Rare knockouts are more interesting than ones due to common variants because the missing gene is more likely to have some effect on biological function if a knocked-out gene has no effects, it is free to accumulate in populations instead of being weeded out by natural selection).

In yet another example of missing gene is the absence of malonyl CoA-acyl carrier protein transacylase, in all isolates except isolate AC544.

An example of a locally missing gene is the PTPS-III family (case number 4 in Table 2) that replaces the folate biosynthesis enzyme FolB in many bacteria and certain eukaryotes [ 39, 40].

When a potential missing gene is found, MaGe provides the curation tools needed for searching for it (TblastN, search translated chromosome sequence using a protein query), and for creating this gene on the query genome (i.e. creation of a new genomic object).

It is possible that the single missing gene is a result of incomplete sequence coverage in the current chimpanzee genome assembly.

Dr. Fischer said he began working on gene therapy for SCID-X1 in 1993, as soon as the missing gene was identified.

During the construction of iCY1106, some missing gene were added from the Vongsangnak's model such as MA-090-247, which encodes an asparaginase (EC: 3.5.1.1), and catalyzes the transformation of L-asparagine into L-aspartate.

For gene prediction software, the percentage of missing genes is strongly correlated with the frequency of gene overlaps.

We also found that the number of missing genes is also affected by the alignment quality in graph-based methods (Fig. 3C).

However, the number of missing genes is similar between the two datasets and higher compared to the 34-species OGs, indicating, once again, the impact of species coverage.