Sentence examples for missing dystrophin with from inspiring English sources

Substituting missing dystrophin with abbreviated microdystrophin has dramatically alleviated disease in mouse DMD models.

For sick kids that might mean producing just enough of the missing dystrophin to stop their muscles from withering.

The progressive fiber damage and membrane leakage are caused by the destabilized dystrophin-associated protein complex (DAPC) due to the missing dystrophin protein.

We apologize that the bibliographic evidence required to put many of our results in context was missing, which, together with the focus on comparing the exogenous human Dystrophin expression with that of the endogenous zebrafish Dystrophin may have misled the reviewer in many ways.

We handled missing covariates with missing indicators.

Dystrophin (light green) is abundant in cardiac muscle from normal mice (left), missing in mice with DMD  center), and partially restored in Duchenne mice treated with CRISPR/Cas9 (right).

Both intramuscular and intraperitoneal administration of an AO-cocktail preferentially induced the in-frame dystrophin transcript missing both exons and partially restored dystrophin protein expression in vivo.

The capacity of human retinal dystrophin (Dp260) to compensate for the missing 427 kDa muscle dystrophin was tested in mdx/utrn−/− mice.

Sarcoglycan complex is also secondarily reduced in Duchenne muscular dystrophy (DMD), when dystrophin is missing [2], indicating that DMD muscle suffers from combined dystrophin and sarcoglycan complex deficiencies [3].

We asked whether the mobile-bound Dystrophin pool observed may result from competition of the exogenous human Dystrophin with endogenous zebrafish Dystrophin.

The general validity of the approach is justified by a comparison of the distribution of the labelled human dystrophin with that of the endogenous zebra fish dystrophin.