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Following this culling, missing data remained minimal throughout the data set (2.8%).
No precise answers were received from the letters sent to corresponding authors; therefore, the number of missing data remained unchanged.
Fortunately, since the GPs keep their electronic medical records (EMR) for a period of at least ten years after patients have died or moved elsewhere, the number of missing data remained very limited.
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Where data are missing, the carry forward technique will be used, which assumes missing data remain constant [42].
For each patient 144 SNPs in candidate genes were determined, after removing monomorphic SNPs and SNPs with more than 20% missing data, 99 SNPs remained and missing data were imputed.
There was no imputation for missing data for the remaining ACR components.
Missing data of the remaining 196 patients were imputed using MI.
Those who had missing values on all items (n=5) were excluded; missing data for the remaining individuals (n=193) were replaced by mode imputation at each item to increase power [ 33].
A limitation of this study is that the missing data for the remaining patients may mean that the two groups were not well matched for albuminuria, a major prognostic factor for renal decline [ 10].
Twenty-nine (74.4%) of the surveyed physician population (n = 39) responded yes to the question: "Did you find the painDETECT Questionnaire useful?" Seven of the other 10 physicians responded no and there were missing data for the remaining three physicians.
The amount of missing data appears to have remained fairly constant over time, as does the proportion of trials that mentioned attempts to avoid missing data.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com