Of these, 291 patients (22.2%) were excluded from this analysis: 164 patients (12.5%) for missing baseline QoL questionnaire, 70 (5.3%) for missing data about supportive drugs and 57 (4.3%) for missing both sets of information.
When comparing the frequency of missing baseline data between the RAOS and the other three questionnaires used, the RAOS had the lowest percentage (1%) of missing values.
We excluded re-admissions and cases with missing baseline data.
Firstly, overall mean scores at baseline substituted missing baseline scores.
There were 258 missing baseline viral loads and 25 missing baseline CD4 counts.
The screening questionnaire, if available, was used in place of a missed baseline assessment.
55 patients were not included for the following reasons: patients' baseline questionnaire missing (n = 15), physicians' baseline questionnaire missing (n = 8), patients' and physicians' baseline questionnaire dated > 30 days apart (n = 15), disease duration < 30 days (n = 13), previous or ongoing use of AM therapy in question (n = 4).
For this analysis, we excluded women with missing date on the baseline questionnaire, women with an erroneous National Registration Number, and women who reported extreme total energy intakes (i.e., 3 standard deviations from the mean value for log-transformed energy).
Briefly, children ≥ 12 years of age by December 2010 (n = 2,153) were excluded to minimize confounding due to tobacco or alcohol consumption, along with children whose parents answered the English or French versions of the study questionnaire (n = 26), and children with missing residential addresses at baseline questionnaire (n = 42) (see Supplemental Material, Figure S1).
Sixteen women were lost to follow-up after the initial meeting and for the present analysis 48 were excluded due to twin pregnancy (n = 6) or because they had missing data on the baseline questionnaire (n = 7) or on one of the three measurements for body weight, dietary intake, estradiol or progesterone levels (n = 35).
