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Therefore, even in patients who do not present with vaginal bleeding, strong suspicion of pregnancy is prudent in order to avoid missing a case of OP.
The cost of missing a case can be high if further spread occurs, and the cost of false-positive diagnosis to the patient, family members, healthcare facility, and community can also be substantial.
Additionally, inherent of an appropriately designed decision analysis or cost-effectiveness analysis, our model incorporates the consequences of undertreatment (missing a case of precancer or cancer) or overtreatment (incorporating costs and some burden of treatment).
In the case of the test that was more specific, but less sensitive, than the standard, its value depends on the harm of missing a case of disease relative to the harm of treating a patient unnecessarily.
In reality, cross diagnosing decrease the risk of missing a case of any of the three potentially life-threatening childhood diseases in the study setting (malaria, pneumonia and diarrhoea).
RDTs have been evaluated extensively for the diagnosis of uncomplicated malaria but not for severe malaria [ 12], and diagnostic test requirements are different in severe disease; eg, a high sensitivity is of utmost importance, because missing a case may result in inappropriate treatment and death.
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These older diagnostics can miss a case of TB in patients with HIV.
Most of these polyps are removed surgically, as a precautionary measure, so as not to miss a case of endometrial cancer.
With the first, you get a quarterly 12-bottle case for £7.49 a bottle, with an opportunity to tweak it or miss a case altogether.
But it is also easy to miss a case which is not untypical or extreme when thinking visually.
Whereas physicians appropriately err on the side of over-diagnosis, thereby assuring they don't miss a case, surveillance case definitions appropriately err on the side of specificity, thereby assuring they do not inadvertently capture illnesses due to other conditions".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com