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In BRCA1, the design coverage was 98.7% with the first 25 bp of coding exon 1 and 42 bp in coding exon 7 omitted as well as some intron-exon boundaries totalling 66 bp of missed sequence.
Except for 1 (2) missed sequence(s), PSfamSearch returned exactly the same results at cutoff π tc (π nc ), but it took only 93.3 (171.2) min; this makes for a speedup of 29.52 16.011).
In BRCA2, the design coverage was 96.1%, with multiple regions within coding exons 4, 5, 7, 8, 9, 10, 11, 12, 14, 15, 18, 19, 21 and 26 missed as well as multiple exon-intron boundaries totaling 408 bp of missed sequence.
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It is also possible that our inventory of metabolic potential has missed sequences related to a specific query gene.
Although PCR tolerates some diversity, sequence conservation between DBL domains of as little as 52% [17] might be responsible for the missed sequences, particularly from colonies directly.
To increase the recall, we induce covariance models for each cluster and scan the dataset to collect missed sequences.
This indicates that some gaps may merely be a consequence of the stringency of the assembly method rather than truly missed sequences.
At the end of "Different from the Others," we're told of a missing sequence in which a great hand descends over a German law book to cross out the entry for Paragraph 175.
There were 169 discordances between the optical map and the pseudomolecules, including missing SwaI sites, extra SwaI sites, missing sequence, extra sequence, complex events, and potential misassembly.
This insertion is performed when the observer, which generated the network evidence E, detected a modification in the TTL or routing path through the packet observations of the missing sequence.
Further analysis revealed that the missing sequence stretch lies within the intron sequence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com