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Exact(7)
Women would rather have a false positive than a missed positive -- a normal mammogram, yet hidden invasive cancer undetected until palpable thus at a later stage.
However, if anything, we observed decreased risks of resistance among HIV-infected patients making it unlikely that we missed positive associations of substantial magnitude.
It seems logical that the benefit of omitting PLND in 50 70% of patients would outweigh the 2 5% of patients with missed positive lymph nodes.
About 38% of the missed positive cases were due to the evidence keywords in the entry (e.g., leverfibrose, hepatomegalie, cholestase) not being picked up by the learning algorithm.
Conversely, a less favorable outcome in patients with lower lymph node yields would then not only be attributable to understaging due to missed positive lymph nodes, but also to tumor intrinsic factors.
Thirty-four cases of CDAD were missed by C. difficile toxin assay results and subsequently identified through chart review (3 missed positive toxins, 26 CDAD patients transferred from other facilities, 3 positive outpatient toxin assays, and 2 diagnosed by colonoscopy), which brought the total number of cases with positive CDAD diagnostics to 696.
Similar(53)
A later report by the Indiana Racing Commission found that Truesdail Laboratories failed to detect a total of seven missed positives – one for a Class 1 drug – over a period of 26 days.
Even though the masking and risk of dense breast tissue have been reported in the scientific literature for more two decades, not one of my health care providers, over a dozen years, ever informed me of all the facts about the limited sensitivity of mammography and the missed positives and the interval cancers caused by dense breast tissue.
In contrast, setting the MINRUN to 3 may be overly conservative and lead to too many missed positives.
Another reason for a missing positive correlation could be EGFR transactivation by other growth factor receptors (Arteaga, 2002).
In any case, for the slaughterhouse study we decided to dilute template DNA if inhibition took place, maybe missing positive samples in return.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com