Never lie to the doctor about missing a dose, since even one missed dose can affect a patient's I.N.R. and cause the doctor to change the weekly dose incorrectly.
"Forgiveness" – the difference between a drug's postdose duration of action and its prescribed dosing interval – estimates the margin of therapeutic effect following a missed dose.
Today, in the health care profession, all types of medication errors including missed dose, wrong dosage forms, wrong time interval, wrong route, etc., are a big deal for better patient care.
With a forgiving drug, the duration of action is much longer than the dosage interval, so an occasional missed dose is unlikely to interrupt therapeutic activity (Osterberg et al. 2010).
The alcohol coupled with a missed dose of anti-seizure medication proved catastrophic.
For the last reported missed dose, each four-week period was classified as adherent or non-adherent, with an adherent period defined as no missed dose reported.
Compliance was defined as ≥85% adherence (no more than one missed dose a week on average) to prescribed treatment.
The first retrieval action is to be conducted by the DOT provider, within 24 hours of a missed dose.
The consequences of a single missed dose would also be less if IPT is repeated soon afterward.
For the purposes of analysis, compliance was defined as 85% or better adherence to the prescribed treatment, equivalent to an average of one missed dose a week.
The last missed dose question does not measure how much ART was missed; rather, it indicates that not all doses were taken and should be interpreted separately.
