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PCR based methods generally have a better detection limit compared to microscopy [11], but both methods likely miss a proportion of clones.
In studies with no confirmatory testing, A1C will seem to miss a proportion of fasting glucose-defined cases of diabetes.
However, a recent study reported a considerable size overlap between CTCs and leukocytes [ 20], so that size-based filter systems probably miss a proportion of CTCs.
Thus, though death certificates may miss a proportion of stroke deaths, those deaths that are identified as stroke deaths are virtually all correct.
A methodological issue in the trials reviewed has been the difficulty in diagnosing 'pure' VaD as the criteria used are relatively insensitive (that is, will miss a proportion of those with significant cerebrovascular disease) and many of those fulfilling probable VaD criteria have mixed pathologies (typically AD and cerebrovascular disease) [ 42].
In the absence of sensitive instruments to detect alcohol misuse in this age group, there is a risk of defining alcohol misuse in young people through the incidence of gross intoxication or hospital admissions due to alcohol poisoning, which might miss a proportion who could potentially benefit from alcohol intervention.
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During the 90 days blanking period, we missed a proportion of events.
Thus, although the Xpert assay missed a proportion of tuberculosis diagnoses, these were typically in patients with less advanced immunodeficiency.
Studies without such linkage will have missed a proportion of these deaths because postdischarge deaths will have been difficult to capture.
There is a considerable risk of missing a proportion of cases of acute UTI in infants and children younger than three years when using dipstick testing, as frequent bladder emptying leads to a lack of urinary nitrite [ 27].
The effect of restricting screening to a subpopulation of high-risk individuals will markedly reduce the cost of screening programmes at the expense of missing a proportion of lung cancers in individuals below the cutoff.
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CEO of Professional Science Editing for Scientists @ prosciediting.com