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This mismatch was exaggerated in low-grade DCIS (15 mm vs 27 mm).
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In this model, inducible mismatches surrounding the mutation site (created by a semi-complementary oligonucleotide in cis- orientation) generated a mismatch 'bubble' that was exaggerated in the mutant sequence relative to the wild-type sequence, which thereby increased the susceptibility of the mutant sequence to DNA strand cleavage by the ssDNA-specific S1 nuclease.
That argument was exaggerated.
Everything they did was exaggerated.
"That alternative was exaggerated".
He was exaggerating.
I hoped she was exaggerating".
Yes, he was exaggerating.
Actually, Stewart was exaggerating.
She was exaggerating a bit.
But Kerry was exaggerating.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com