Sentence examples for mismapped from inspiring English sources

Assuming that the LD between a mismapped SNP and its direct neighbors is low, a mismapped SNP is imputed by chance and therefore its error rate is related to its MAF.

Through comparison of the first (including matches to the reverse-complement strand) and the second mapping statistics, the amount of mismapped reads was determined.

If a read maps best to a given location relative to the other CALs, it is considered 'mapped' and may thus inflate the error rate if indeed mismapped.

Applying the different filters again identifies all of them as belonging to one of the four categories: genuine paternal allele, mismapped splice junction, mismapped paralog sequence, and genomic variation annotated in the SNP database.

Imputation error rate was computed for each SNP in order to detect SNPs that were mismapped in the UMD3.1 assembly.

We exclude clusters consisting of only one element because they are likely to be a product of mismapped reads or sequencing errors.

It seems that the ratio between the number of reads calling the reference base versus the number of mismapped reads calling variants can confound the variant calling algorithms.

The majority of false positive mutation calls are generated from mismapped reads, for example, paralogs were mistakenly mapped to a single locus.

In this case, heterozygous genotypes could be mismapped to the wrong side of the CO and possibly mimic a NCO tract.

To avoid errors from mismapped reads, we restricted our panels to sites where all overlapping 35mers are unique across hg19 according to the Duke Uniq 35 track from the Mappability tracks on the UCSC Genome Browser [ 36].

Where the RNA-seq data are either insufficient or irrelevant, pseudogenes (or genes which are members of families containing pseudogenes) may contain mismapped reads for the non-functional copies that can produce false positive mutation calls.