In case these 2 distinct dsRNAs are used, their common phenotype induced by down-regulation of their shared off-target gene may lead to misinterpretation of the experiment.
Much of the "debate" regarding the affects of nutrition on cashmere production arises from the misinterpretation of both experiments that did not detect statistically significant effects and of experiments that did detect statistically significant effects.
This may lead to misinterpretation of MP-based experiments on cellular PS uptake if proper controls are not included [ 8].
We had found previously that the use of littermate control mice is essential to avoid misinterpretation of MCA carcinogenesis experiments [ 26, 27, 30].
"If you're living in a poor neighborhood deprived of options, there's a certain rationality to keep taking a drug that will give you some temporary pleasure," Dr. Hart said in an interview, arguing that the caricature of enslaved crack addicts comes from a misinterpretation of the famous rat experiments.
Similarly, a previous statistical cognition experiment showed misinterpretation of forest plots (i.e., graphs representing the results of meta-analyses) with an average of 42 out of 63 questions answered correctly (67 %) among 279 researchers with experience in meta-analysis [ 18].
This is a massive misinterpretation of data, because there is no experiment showing a cause-effect relationship between looping and gene activity, only a correlation.
These secondary structures may therefore compete with the intended target for effective probe annealing in a microarray experiment, resulting in a misinterpretation of the amount of target present in the sample.
Poor or, even worse, no labelling has an unremarkable ability to cause misinterpretation of results and unnecessary repeating of perfectly good experiments.
Here, we would like to further explain the experiments performed to avoid possible misinterpretation of the results.
