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This may have introduced some misclassification of physical activity status.
For example, if the claim was filed after assessment of physical job exposures (survey administration), misclassification of physical job demands is likely to be independent of WC filing.
However, the lack of repeated measures of physical fitness during the relatively long follow-up period may contribute to misclassification of physical fitness.
The effect of misclassification of physical activity would have been to decrease the ability of the study to demonstrate an effect of physical activity on endometrial cancer risk.
This potential (non-differential) misclassification of physical activity is, however, unlikely to explain the opposite direction of the estimated relative risk among the most active obese persons when compared with the normal-weight or obese sedentary persons.
However, because our physical activity assessment preceded the diagnosis of breast cancer, potential misclassification of physical activity would have tended to be non-differential with respect to disease status, which would have resulted in an attenuation of the true association.
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Another limitation of our study includes the potential misclassification of participants' physical activity levels based on occupational physical activity, as individuals who did not report current occupational activity were included in the lowest occupational activity category for the Cambridge index (Table 1b).
Additionally, incorrect geocoding may bias the results of spatial analysis, resulting in misclassification of actual physical locations that may adversely affect research outcomes or location-based business decisions [14, 15].
Therefore, there may have been greater misclassification of the physical health outcomes, possibly leading to an underestimation of their contribution to dependency.
For the prospective studies in our analysis, misclassification of prepregnancy physical activity in the prospective studies is likely to be random with respect to exposure, because women were unaware of their GDM diagnosis at the time of assessment; however, attenuation of the effect estimates may lead to an underestimation of the true association.
Although there is a risk of misclassification of level of physical activity, its impact is estimated to be limited.
More suggestions(12)
misclassification of infected
misclassification of cumulative
misclassification of final
misclassification of only
misclassification of patient
misclassification of such
misclassification of other
misclassification of legitimate
misclassification of current
misclassification of individual
misclassification of resources
misclassification of adults
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