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The consequence of this conceivable misclassification of our exposures would tend to bias the results toward the null hypothesis.
This may be particularly important for postpartum depression: we assessed postpartum depression at 6 months, but the prevalence of postpartum depression is highest in the 2nd and 3rd months postpartum.[21] Misclassification of our exposure is likely nondifferential with respect to the outcomes, which would attenuate results towards the null.
The extent of bias resulting from misclassification of our algorithm is described in Table 6.
An important limitation of our study is the potential for misclassification of our key exposure variables.
Hence, in this study, the possible misclassification of our ethnic groups should not be a serious problem.
However, misclassification of our control patients cannot be excluded, since our criteria for the clinical diagnosis of large-vessel vasculitis were relatively strict.
Similar(45)
For example, the misclassification rate of our model remained close to 30%% both during training and during intraspecies and inter-species validation.
But, because not all source/intake locations fell within block groups that intersect with service area boundaries of CWSs [ 31], this could lead to misclassification error of our demographic variables.
It should be stated, however, that we did not use the most reliable method for counting SFU, the automated ELISPOT plate reader, and therefore misclassification of some of our results can not be ruled out.
24 However, variability in this test has been found among healthy elderly subjects as well, 61 which may have led to misclassification of some of our subjects and, thus, affected the results.
The potential exists for misclassification of race/ethnicity in our cohort due to possible information bias via variation in data gathering practices, i.e., self-identification versus racial classification by hospital staff.
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