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The rate of misclassification of diagnoses is therefore unknown.
Underreporting or misclassification of diagnoses by hospital physicians without confirmatory tests may also have occurred.
Information on disease diagnosis was based on self-reporting, which may have led to a misclassification of diagnoses.
We would expect misclassification of diagnoses to affect estimates for specific injury codes more than the overall estimates for all soft-tissue knee injury codes combined.
Bias from misclassification of diagnoses was unlikely because accuracy and completeness of records in general practices is high (Hippisley-Cox et al, 2003; Herrett et al, 2010).
The predictive value of computer-detected IS/TIA is lower than that for other outcomes such as MI owing to the level of misclassification of diagnoses using Read codes.
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Misclassification of final diagnoses and the potential for underestimating the frequency of delayed presentations of serious neurologic disease is possible.
However, it is unlikely that such misclassification of discharge diagnoses could explain the temporal tracking of CVD syndromic events with CVD hospital discharge ICD-9 discharge codes.
Restricting the analysis to only confirmed events provided a quantitative assessment of the consequence of misclassification of some diagnoses on risk estimates.
A general limitation of using state and federal administrative hospital discharge databases is the potential misclassification of both diagnoses and procedures which are typically coded using ICD-9-CM.
First, there may be some misclassification of cancer diagnoses because we did not send for medical records for breast cancer case patients to get a final confirmation of the cancer, e.g., via histology.
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CEO of Professional Science Editing for Scientists @ prosciediting.com