It is believed that those features keep under-reporting and misclassification is very low.
Additionally, differential misclassification of the modes of labor onset and the occurrence of preterm prelabor rupture of membranes is believed to be minimal and unlikely to affect the observed associations.
In the 1950 1960s, identification relied upon morphology using light microscopy (Engell, 1959), but many of the identified cells are believed to be false positives due to artifacts of preparation and by the misclassification of leukocyte precursors (Christopherson, 1965).
DOL has indicated that it believes misclassification is particularly rampant in certain industries, including construction, child and home health care, transportation and warehousing, janitorial, and meat and poultry processing, among others.
DOL has explained that it believes misclassification is a significant problem which deprives many workers access to federal, state and local benefits and protections, such as family/medical leave, overtime, minimum wage, unemployment compensation and protection under employment anti-discrimination laws.
We believe this misclassification is likely to be nondifferential and therefore likely to underestimate the true associations.
Considering this, and that there is no prevailing belief that indoor smoke exposure from biomass-burning stoves or kerosene-burning stoves or lamps is related to TB occurrence, we believe exposure misclassification is likely to be minimal.
As explained below, we believe that substantial misclassification is unlikely; even if misclassification did occur, it would most likely be nondifferential with regard to exposure, which would be expected to bias associations toward the null rather than create spurious relationships.
