To aid interpretation, metabolites were grouped into 11 biological categories: amino acid and related; carbohydrates and related; catecholamines and related; complex lipids and related; energy metabolism and organic acids; fatty acids (free and from lipids); purines, pyrimidines and related; steroids and related; vitamins, cofactors and related; miscellaneous; and unknown metabolites.
Beside genes encoding miscellaneous and unknown proteins which were the most numerous, genes related to defense-associated proteins and hormonal synthesis and response, were well represented.
The review also identifies the primary neonatal cause of death in the same way; these are categorised under immaturity related, hypoxia, infection, congenital abnormalities, trauma, miscellaneous and unknown cause of death.
Types of CT examinations were grouped into six categories (head (including 470 scans of the neck), chest, abdomen/pelvis, spine, extremities and miscellaneous or unknown) based on those suggested by Mettler et al [ 16].
In this study, above broad causes of death were focused and for further analyses, other causes like maternal and perinatal condition (including nutritional cause), miscellaneous, and unknown causes were not used.
The tra/trb cluster is separated from the chemolithoautotrophy module by two regions (25.2 and 29.6 kb) with miscellaneous or mostly unknown functions.
Among the 133 phosphorylation sites listed in Figure 3, only one phosphorylation site, namely Ser720 of AKAP2 shown opposite change in protein phosphorylation (see the first entry in the Unknown Miscellaneous category).
The majority of the rest of the genes were lumped into an unknown and miscellaneous category.
Sows/gilts that got the primary finding trauma miscellaneous, circulatory/cardiac failure or unknown were in most cases found dead without any previous observed symptoms.
The final diagnoses in 33 patients with no presumptive treatment and positive PCR results were infection other than PCP (bacterial pneumonia, n = 5; aspergillosis, n = 3; atypical pneumonia, n = 1; tuberculosis, n = 1; viral pneumonia, n = 1), interstitial pneumonia associated with collagen diseases (n = 8), drug-induced pneumonia (n = 5), miscellaneous (n = 4), and unknown etiology (n = 5).
