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19 patients (41%) had poor risk cytogenetics, 11 patients (24% ) normal karyotype, 9 patients (20%) miscellaneous abnormalities, and 7 patients (15%) unknown cytogenetics as defined by CALGB criteria.
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Despite the small sample size, histone acetylation was a significant prognostic factor for patients with normal and miscellaneous cytogenetic abnormalities on both univariate and multivariate analysis.
Of the entire sample, 50.2% had no chronic respiratory diseases or symptoms, with normal spirometry; whereas 5.6% had significant post-bronchodilator reversibility on spirometry, with clinical features suggestive of asthma, 12.9% had restrictive pattern, and 22.1% had miscellaneous symptoms and abnormalities on spirometry.
The review also identifies the primary neonatal cause of death in the same way; these are categorised under immaturity related, hypoxia, infection, congenital abnormalities, trauma, miscellaneous and unknown cause of death.
There were three transfers for APH/PPROM, all classified as PPROM; one APH/fetal abnormality classified as miscellaneous; one APH/PTL classified as PTL; one IUGR/fetal abnormality classified as fetal abnormality; one fetal abnormality/PTL classified as PTL; one PET/APH classified as PET; one PET/IUGR classified as PET; and one PPROM/PTL classified as PTL.
We found no appreciable difference in mortality (Fig. 1B and supplementary material Fig. S1), Mpi activity (supplementary material Table S2) or morphology between uninjected larvae and those injected with 6.7 ng of control morpholino, and less than 10% of either uninjected or control-morpholino-injected embryos displayed any developmental delay or visible abnormality (categorized as miscellaneous).
[ 8] sorted 101 dogs with FUO into 6 main groups with the following result: infections 16%, neoplasia 9.5%, immune-mediated disease 22%, miscellaneous conditions 11.5%, primary bone marrow abnormalities 22%, and true FUO 19%.
The remaining cytogenetic abnormalities were characterized as normal or miscellaneous (any other abnormality).
Conditions were grouped as follows: all-cause disabling chronic conditions; psychological disorders; intellectual disability; sensory impairments; congenital abnormalities; specific conditions, such as asthma, cerebral palsy and epilepsy; and a miscellaneous group of conditions with insufficient numbers for entry into meta-analysis (table 1).
Age: Miscellaneous.
Other miscellaneous brief notes.
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